Hiroko Tsukamura Selected Research

AIDS-Related Complex (ARC)

6/2022	Central somatostatin-somatostatin receptor 2 signaling mediates lactational suppression of luteinizing hormone release via the inhibition of glutamatergic interneurons during late lactation in rats.
1/2022	Kobayashi Award 2019: The neuroendocrine regulation of the mammalian reproduction.
8/2021	Reduction of arcuate kappa-opioid receptor-expressing cells increased luteinizing hormone pulse frequency in female rats.
8/2021	Kisspeptin Neurons and Estrogen-Estrogen Receptor α Signaling: Unraveling the Mystery of Steroid Feedback System Regulating Mammalian Reproduction.
1/2021	Effect of diet-induced obesity on kisspeptin-neurokinin B-dynorphin A neurons in the arcuate nucleus and luteinizing hormone secretion in sex hormone-primed male and female rats.
1/2021	Morphological Analysis of the Hindbrain Glucose Sensor-Hypothalamic Neural Pathway Activated by Hindbrain Glucoprivation.
12/2020	Mating-induced increase in Kiss1 mRNA expression in the anteroventral periventricular nucleus prior to an increase in LH and testosterone release in male rats.
11/2020	Paraventricular Dynorphin A Neurons Mediate LH Pulse Suppression Induced by Hindbrain Glucoprivation in Female Rats.
8/2020	Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice.
8/2020	Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats.

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Hiroko Tsukamura Research Topics

Disease

34	AIDS-Related Complex (ARC) 06/2022 - 10/2005
5	Malnutrition (Nutritional Deficiencies) 01/2022 - 06/2015
2	Infertility (Sterility) 01/2022 - 08/2020
1	Obesity 01/2021
1	Atrophy 08/2020
1	Body Weight (Weight, Body) 08/2020
1	Infections 01/2020
1	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2020
1	Male Infertility (Male Sterility) 01/2019
1	Neuroblastoma 10/2013
1	Pheochromocytoma 10/2011
1	Ketosis 06/2011
1	Hyperglycemia 03/2011
1	Starvation 03/2011
1	Hyperphagia (Overeating) 03/2011
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 03/2011
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 10/2004
1	Pituitary Neoplasms (Pituitary Adenoma) 10/2004

Drug/Important Bio-Agent (IBA)

31	KisspeptinsIBA 06/2022 - 10/2005
25	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2022 - 10/2005
15	Estrogens (Estrogen)FDA Link 01/2022 - 10/2004
11	GonadotropinsIBA 01/2022 - 06/2011
11	Neurokinin BIBA 08/2021 - 02/2010
11	Dynorphins (Dynorphin)IBA 08/2021 - 02/2010
10	Luteinizing Hormone (Lutropin)FDA LinkGeneric 06/2022 - 01/2009
8	Messenger RNA (mRNA)IBA 01/2021 - 04/2007
3	Glucose (Dextrose)FDA LinkGeneric 10/2021 - 11/2020
3	Estrogen ReceptorsIBA 01/2015 - 10/2005
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 06/2022 - 04/2020
2	Deoxyglucose (2 Deoxy D glucose)IBA 10/2021 - 11/2020
2	Corticotropin-Releasing HormoneIBA 01/2021 - 04/2019
2	SteroidsIBA 01/2021 - 01/2009
2	Histones (Histone)IBA 04/2020 - 05/2012
2	Hormones (Hormone)IBA 01/2020 - 10/2004
2	Testosterone (Sustanon)FDA Link 01/2020 - 10/2004
2	Estrogen Receptor alphaIBA 01/2017 - 04/2007
2	KetonesIBA 06/2011 - 03/2011
1	N-Methylaspartate (NMDA)IBA 06/2022
1	EndorphinsIBA 10/2021
1	Opioid Receptors (Opioid Receptor)IBA 10/2021
1	SaporinsIBA 08/2021
1	Dopamine (Intropin)FDA LinkGeneric 01/2021
1	Mixed Function Oxygenases (Monooxygenases)IBA 01/2021
1	Proto-Oncogene Proteins c-fos (FRAs)IBA 01/2021
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2021
1	Neuropeptide YIBA 01/2021
1	Cre recombinaseIBA 08/2020
1	Retinoblastoma-Binding Protein 7IBA 04/2020
1	RNA (Ribonucleic Acid)IBA 04/2020
1	Tumor Viral Antigens (Large T Antigen)IBA 01/2020
1	tdTomatoIBA 04/2019
1	Agouti-Related ProteinIBA 01/2019
1	NeuropeptidesIBA 01/2019
1	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2019
1	Calcitonin Receptors (Calcitonin Receptor)IBA 04/2018
1	CholesterolIBA 01/2015
1	ChromatinIBA 01/2015
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2015
1	LuciferasesIBA 10/2013
1	DNA (Deoxyribonucleic Acid)IBA 10/2013
1	NucleotidesIBA 10/2011
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 03/2011
1	Ketone BodiesIBA 03/2011
1	Fatty Acids (Saturated Fatty Acids)IBA 03/2011
1	Complementary DNA (cDNA)IBA 10/2004
1	Ataxin-1IBA 10/2004

Therapy/Procedure

2	Ovariectomy (Oophorectomy) 01/2017 - 04/2007
1	Injections 08/2020
1	Castration 10/2004